HitPredict

Interactor 1: SHAN1 (D3YZU1)
SH3 and multiple ankyrin repeat domains protein 1 (Shank1)
Gene: Shank1

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873, 36604605, 19455133
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1, PDZ~PDZ_6, PDZ~SAM_1, Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_1~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0030425 - dendrite
GO:0035176 - social behavior
and 16 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2167
Mm

1 724
+ Rn
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Rn
+ Hs
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024