Interactor 1: WDR4 (P57081)
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein Wuho homolog) (hWH) (WD repeat-containing protein 4)
Gene: WDR4
Interactor 2: TRMB (Q9UBP6)
tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (mRNA (guanine-N(7)-)-methyltransferase) (EC 2.1.1.-) (miRNA (guanine-N(7)-)-methyltransferase) (EC 2.1.1.-) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase)
Gene: METTL1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.760 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15861136, 26751069, 33961781, 25416956, 26186194, 16189514, 28514442, 32296183, 36599982, 36599985, unassigned1304, 31515488 |
| Identification Methods | affinity chromatography technology, two hybrid, x-ray crystallography, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006400 - tRNA modification GO:0043527 - tRNA methyltransferase complex and 2 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
