HitPredict

Interactor 1: SYJ2B (P57105)
Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25)
Gene: SYNJ2BP

Interactor 2: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	10827173
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007268 - chemical synaptic transmission
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 145 Hs			1 963
+	Hs
		942339 DLG4_HUMAN (3-142): 4.24e-27: 106: 31.94		LRP8_HUMAN (1-963): 0: 814: 100.00
+	Dm
		113371 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		Q9VBN2_DROME (5-286): 9.11e-28: 123: 23.57
+	Mm
		1143476 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		LRP8_MOUSE (4-333): 1.96e-29: 128: 27.04
+	Mm
		69882 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		B1AXJ3_MOUSE (5-230): 2.86e-23: 108: 17.30
+	Hs
		883907 SYJ2B_HUMAN (1-145): 1.52e-45: 147: 100.00		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Mm
		1265297 SYJ2B_MOUSE (1-145): 6.21e-45: 145: 91.03		LRP1_MOUSE (690-894): 6.6e-10: 65.6: 11.16
+	Mm
		57561 SYJ2B_MOUSE (1-145): 6.21e-45: 145: 91.03		LRP2_MOUSE (195-462): 9.58e-10: 65.3: 17.36
+	Hs
		883908 SYJ2B_HUMAN (1-145): 1.52e-45: 147: 100.00		LRP1_HUMAN (5-257): 6.13e-09: 62.6: 13.53
+	Dm
		113267 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		Q8IRV8_DROME (140-254): 2.79e-16: 86.7: 39.52
+	Mm
		57225 A2AKD7_MOUSE (7-141): 5.86e-28: 108: 25.00		NID1_MOUSE (75-308): 5.38e-15: 82.2: 14.46
+	Dm
		113773 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		Q9W4Y3_DROME (151-333): 1.12e-11: 71.6: 28.00
+	Mm
		1267815 SNTG2_MOUSE (3-144): 2.89e-31: 118: 23.38		LRP1B_MOUSE (6-248): 8.96e-09: 61.8: 14.34
+	Hs
		942324 DLG4_HUMAN (3-142): 4.24e-27: 106: 31.94		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Hs
		957608 DLG2_HUMAN (6-142): 7.86e-27: 106: 29.79		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Mm
		1143471 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		LRP1_MOUSE (690-894): 6.6e-10: 65.6: 11.16
+	Mm
		57555 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		LRP2_MOUSE (195-462): 9.58e-10: 65.3: 17.36
+	Hs
		942331 DLG4_HUMAN (3-142): 4.24e-27: 106: 31.94		LRP1_HUMAN (5-257): 6.13e-09: 62.6: 13.53
+	Hs
		957631 DLG3_HUMAN (1-121): 2.05e-23: 96.6: 38.84		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03