HitPredict

Interactor 1: GEMI4 (P57678)
Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97)
Gene: GEMIN4

Interactor 2: RUXG (P62308)
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
Gene: SNRPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0030532 - small nuclear ribonucleoprotein complex GO:0034719 - SMN-Sm protein complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1058 Hs			1 76
+	Hs
		68406 GEMI4_HUMAN (1-1058): 0: 2100: 100.00		RUXGL_HUMAN (1-76): 7.68e-29: 99.4: 94.74
+	Hs
		883969 GEMI4_HUMAN (1-1058): 0: 2100: 100.00		RSMN_HUMAN (1-70): 1.26e-22: 88.2: 21.25
+	Hs
		883966 GEMI4_HUMAN (1-1058): 0: 2100: 100.00		RUXF_HUMAN (5-73): 4.25e-24: 87.8: 24.64
+	Hs
		538881 GEMI4_HUMAN (1-1058): 0: 2100: 100.00		RSMB_HUMAN (1-70): 6.75e-22: 86.3: 21.25
+	Hs
		167674 GEMI4_HUMAN (1-1058): 0: 2100: 100.00		LSM1_HUMAN (13-74): 7.23e-18: 73.3: 33.85