HitPredict

Interactor 1: KLF3 (P57682)
Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2)
Gene: KLF3

Interactor 2: MCAF1 (Q6VMQ6)
Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621)
Gene: ATF7IP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 1270
+	Hs
		316921 KLF8_HUMAN (1-342): 9.85e-87: 267: 36.99		MCAF1_HUMAN (1-1270): 3.52e-174: 552: 100.00
+	Hs
		1167140 KLF12_HUMAN (239-345): 1.44e-52: 180: 83.18		MCAF1_HUMAN (1-1270): 3.52e-174: 552: 100.00
+	Hs
		435126 SP1_HUMAN (256-342): 6.19e-26: 110: 57.47		MCAF1_HUMAN (1-1270): 3.52e-174: 552: 100.00
+	Hs
		1167122 ZN350_HUMAN (67-255): 1.4e-25: 109: 7.77		MCAF1_HUMAN (1-1270): 3.52e-174: 552: 100.00
+	Hs
		317017 KLF8_HUMAN (1-342): 9.85e-87: 267: 36.99		CHD7_HUMAN (650-1177): 7.42e-32: 138: 12.63
+	Hs
		152621 KLF3_HUMAN (1-345): 4.46e-98: 295: 100.00		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		152569 KLF8_HUMAN (1-342): 9.85e-87: 267: 36.99		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		1350247 KLF12_HUMAN (239-345): 1.44e-52: 180: 83.18		CHD7_HUMAN (650-1177): 7.42e-32: 138: 12.63
+	Hs
		1046715 KLF5_HUMAN (217-342): 5.6e-39: 145: 63.36		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		204195 KLF4_HUMAN (223-342): 2.87e-35: 136: 60.00		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		1315379 KLF16_HUMAN (260-342): 1.23e-29: 115: 63.86		CHD7_HUMAN (650-1177): 7.42e-32: 138: 12.63
+	Hs
		1243850 KLF15_HUMAN (258-342): 8.09e-30: 119: 63.53		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		435120 SP1_HUMAN (256-342): 6.19e-26: 110: 57.47		MCAF2_HUMAN (1062-1260): 3.6e-26: 118: 31.93
+	Hs
		152643 KLF5_HUMAN (217-342): 5.6e-39: 145: 63.36		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		1056958 ZN251_HUMAN (18-200): 2.14e-33: 132: 7.27		MDC1_HUMAN (663-1169): 2.42e-11: 70.8: 17.22
+	Hs
		152558 KLF4_HUMAN (223-342): 2.87e-35: 136: 60.00		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		152697 KLF15_HUMAN (258-342): 8.09e-30: 119: 63.53		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		152686 KLF16_HUMAN (260-342): 1.23e-29: 115: 63.86		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Rn
		94373 WT1_RAT (267-314): 6.91e-09: 58.9: 54.90		F1M9G7_RAT (641-1166): 4.04e-13: 76.6: 14.55