Interactor 1: NICA (P57716)
Nicastrin
Gene: Ncstn

Interactor 2: PEN2 (Q9CQR7)
Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2)
Gene: Psenen

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 16449386
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ncstrn_small~PEN-2
Common GO terms GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
and 12 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 708
Mm

1 101
+ Hs
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024