HitPredict

Interactor 1: PCBP3 (P57721)
Poly(rC)-binding protein 3 (Alpha-CP3) (PCBP3-overlapping transcript) (PCBP3-overlapping transcript 1)
Gene: PCBP3

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	34133714, 17643375
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome GO:1990904 - ribonucleoprotein complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 371 Hs			1 456
+	Hs
		884369 PCBP3_HUMAN (1-371): 6.1e-122: 358: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		1072211 PCBP2_HUMAN (33-370): 2.85e-88: 272: 69.17		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1072210 PCBP2_HUMAN (33-370): 2.85e-88: 272: 69.17		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Sc
		745022 PBP2_YEAST (38-362): 1.71e-80: 253: 28.04		RUVB2_YEAST (5-455): 0: 627: 41.72
+	Hs
		1072071 PCBP1_HUMAN (280-369): 7.33e-14: 74: 30.77		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1072070 PCBP1_HUMAN (280-369): 7.33e-14: 74: 30.77		RUVB2_HUMAN (2-455): 0: 651: 42.76