HitPredict

Interactor 1: TMPS3 (P57727)
Transmembrane protease serine 3 (EC 3.4.21.-) (Serine protease TADG-12) (Tumor-associated differentially-expressed gene 12 protein)
Gene: TMPRSS3

Interactor 2: TOR3A (Q9H497)
Torsin-3A (ATP-dependent interferon-responsive protein) (Torsin family 3 member A)
Gene: TOR3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 397
+	Hs
		1316654 TMPSD_HUMAN (53-449): 2.32e-113: 347: 37.04		TOR3A_HUMAN (1-397): 8.17e-144: 416: 100.00
+	Hs
		1330730 ST14_HUMAN (72-449): 4.39e-108: 340: 29.23		TOR3A_HUMAN (1-397): 8.17e-144: 416: 100.00
+	Hs
		371472 KLKB1_HUMAN (24-453): 5.44e-104: 324: 28.05		TOR3A_HUMAN (1-397): 8.17e-144: 416: 100.00
+	Hs
		409559 HEPS_HUMAN (119-449): 2.21e-98: 303: 37.43		TOR3A_HUMAN (1-397): 8.17e-144: 416: 100.00
+	Hs
		1330327 TMPS5_HUMAN (118-452): 2.7e-97: 301: 40.53		TOR3A_HUMAN (1-397): 8.17e-144: 416: 100.00
+	Hs
		341292 FA9_HUMAN (72-449): 4.43e-94: 293: 25.71		TOR3A_HUMAN (1-397): 8.17e-144: 416: 100.00
+	Hs
		152037 TMPSD_HUMAN (53-449): 2.32e-113: 347: 37.04		TOR1A_HUMAN (81-395): 5.18e-119: 350: 38.10
+	Hs
		152058 ST14_HUMAN (72-449): 4.39e-108: 340: 29.23		TOR1A_HUMAN (81-395): 5.18e-119: 350: 38.10
+	Hs
		1128311 ST14_HUMAN (72-449): 4.39e-108: 340: 29.23		TOR2A_HUMAN (99-396): 1.62e-108: 323: 36.58
+	Hs
		151960 HEPS_HUMAN (119-449): 2.21e-98: 303: 37.43		TOR1A_HUMAN (81-395): 5.18e-119: 350: 38.10
+	Hs
		409523 HEPS_HUMAN (119-449): 2.21e-98: 303: 37.43		TOR2A_HUMAN (99-396): 1.62e-108: 323: 36.58
+	Hs
		1231544 ST14_HUMAN (72-449): 4.39e-108: 340: 29.23		TOR2X_HUMAN (99-272): 3.93e-72: 227: 36.78
+	Hs
		409536 HEPS_HUMAN (119-449): 2.21e-98: 303: 37.43		TOR2X_HUMAN (99-272): 3.93e-72: 227: 36.78