HitPredict

Interactor 1: TMPS3 (P57727)
Transmembrane protease serine 3 (EC 3.4.21.-) (Serine protease TADG-12) (Tumor-associated differentially-expressed gene 12 protein)
Gene: TMPRSS3

Interactor 2: ALG9 (Q9H6U8)
Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase)
Gene: ALG9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 611
+	Hs
		1316657 TMPSD_HUMAN (53-449): 2.32e-113: 347: 37.04		ALG9_HUMAN (1-611): 0: 693: 100.00
+	Hs
		1332543 ST14_HUMAN (72-449): 4.39e-108: 340: 29.23		ALG9_HUMAN (1-611): 0: 693: 100.00
+	Hs
		409560 HEPS_HUMAN (119-449): 2.21e-98: 303: 37.43		ALG9_HUMAN (1-611): 0: 693: 100.00
+	Hs
		1332544 TEST_HUMAN (207-451): 5.85e-99: 300: 38.37		ALG9_HUMAN (1-611): 0: 693: 100.00
+	Hs
		1313401 ST14_HUMAN (72-449): 4.39e-108: 340: 29.23		ALG12_HUMAN (66-449): 1.59e-74: 248: 17.60