HitPredict

Interactor 1: RAB25 (P57735)
Ras-related protein Rab-25 (CATX-8)
Gene: RAB25

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0055037 - recycling endosome GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 216
+	Ce
		185001 Q9UAQ6_CAEEL (1-210): 3.44e-89: 262: 40.95		RAN_CAEEL (3-205): 3.44e-97: 283: 88.18
+	Hs
		918874 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19
+	Mm
		918986 RAB1A_MOUSE (1-210): 3.08e-89: 262: 39.05		RAB35_MOUSE (6-188): 1.31e-87: 258: 29.19
+	Zm
		73944 B4FAE1_MAIZE (6-211): 2.22e-90: 265: 40.78		B4FAE1_MAIZE (4-208): 1.07e-84: 251: 27.89
+	Hs
		918846 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		918879 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		918944 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72
+	Mm
		919000 RAB1A_MOUSE (1-210): 3.08e-89: 262: 39.05		RAB1B_MOUSE (4-196): 1.67e-80: 240: 28.57
+	Hs
		1079964 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72
+	Hs
		894715 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76
+	Hs
		894712 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76
+	Hs
		913992 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Hs
		914093 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Hs
		913989 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Hs
		844947 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		895472 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14
+	Hs
		591801 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB4A_HUMAN (11-169): 1.53e-27: 105: 34.57
+	Hs
		844859 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		591800 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB4A_HUMAN (11-169): 1.53e-27: 105: 34.57