HitPredict

Interactor 1: NU107 (P57740)
Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107)
Gene: NUP107

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	26496610, 15146057, 24927568, 20676042, 17360435
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005829 - cytosol GO:0006913 - nucleocytoplasmic transport and 1 others more... GO:0031080 - nuclear pore outer ring
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 925 Hs			1 360
+	Hs
		884770 NU107_HUMAN (1-925): 0: 1379: 100.00		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		884696 NU107_HUMAN (1-925): 0: 1379: 100.00		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		878162 NU107_HUMAN (1-925): 0: 1379: 100.00		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Hs
		152864 NU107_HUMAN (1-925): 0: 1379: 100.00		APAF_HUMAN (78-318): 4.09e-09: 60.2: 13.89
+	Sc
		857044 NUP84_YEAST (148-910): 3.36e-160: 488: 19.60		SEC13_YEAST (7-319): 1.17e-73: 232: 29.84
+	Sc
		857031 NUP84_YEAST (148-910): 3.36e-160: 488: 19.60		SEH1_YEAST (185-338): 3.3e-10: 62.7: 16.05