HitPredict

Interactor 1: LSM3 (P57743)
U6 snRNA-associated Sm-like protein LSm3 (SmX4 protein)
Gene: LSM3

Interactor 2: RU2A (Q08963)
U2 small nuclear ribonucleoprotein A' (U2 snRNP A') (Looks exceptionally like U2A protein 1)
Gene: LEA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	LRR_9~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 89 Sc			1 238
+	Dm
		1359984 SMD2_DROME (4-76): 1.61e-20: 80.2: 30.49		RU2A_DROME (1-237): 1.29e-45: 154: 21.55
+	Sp
		1013609 RSMB_SCHPO (12-86): 7.35e-21: 81.8: 28.05		RU2A_SCHPO (32-237): 4.63e-41: 142: 27.27
+	Hs
		453796 RSMN_HUMAN (10-86): 1.36e-24: 93.7: 26.51		RU2A_HUMAN (32-237): 1.94e-35: 128: 23.08
+	Hs
		453752 RSMB_HUMAN (10-86): 3.53e-24: 92.9: 26.51		RU2A_HUMAN (32-237): 1.94e-35: 128: 23.08
+	Sp
		144212 SMD2_SCHPO (4-77): 3.86e-19: 76.8: 26.83		RU2A_SCHPO (32-237): 4.63e-41: 142: 27.27
+	Hs
		453792 SMD2_HUMAN (4-76): 1.47e-20: 80.2: 28.05		RU2A_HUMAN (32-237): 1.94e-35: 128: 23.08
+	Hs
		453790 RUXG_HUMAN (8-81): 2.24e-20: 78.7: 27.03		RU2A_HUMAN (32-237): 1.94e-35: 128: 23.08
+	Sc
		865987 LSM7_YEAST (2-83): 1.07e-20: 80.6: 30.23		RU2A_YEAST (1-238): 4.3e-35: 126: 91.74
+	Sc
		986605 SMD2_YEAST (4-76): 1.35e-20: 80.2: 30.67		RU2A_YEAST (1-238): 4.3e-35: 126: 91.74
+	Hs
		538998 RSMB_HUMAN (10-86): 3.53e-24: 92.9: 26.51		LRRK2_HUMAN (1-157): 3.83e-19: 88: 14.13
+	Hs
		912481 SMD2_HUMAN (4-76): 1.47e-20: 80.2: 28.05		LRRK2_HUMAN (1-157): 3.83e-19: 88: 14.13