HitPredict - High confidence protein-protein interactions

Interactor 1: PCNA (P57761)
Proliferating cell nuclear antigen (PCNA)
Gene: PCNA

Interactor 2: PCNA (P57761)
Proliferating cell nuclear antigen (PCNA)
Gene: PCNA

Species: Cricetulus griseus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Interacting Pfam domains	PCNA_C~PCNA_C, PCNA_C~PCNA_N, PCNA_N~PCNA_N
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0000701 - purine-specific mismatch base pair DNA N-glycosylase activity GO:0000785 - chromatin GO:0001673 - male germ cell nucleus and 26 others more... GO:0003682 - chromatin binding GO:0003684 - damaged DNA binding GO:0005652 - nuclear lamina GO:0005813 - centrosome GO:0006272 - leading strand elongation GO:0006287 - base-excision repair, gap-filling GO:0006298 - mismatch repair GO:0016604 - nuclear body GO:0019985 - translesion synthesis GO:0030337 - DNA polymerase processivity factor activity GO:0030855 - epithelial cell differentiation GO:0030971 - receptor tyrosine kinase binding GO:0031297 - replication fork processing GO:0032077 - positive regulation of deoxyribonuclease activity GO:0032139 - dinucleotide insertion or deletion binding GO:0032405 - MutLalpha complex binding GO:0034644 - cellular response to UV GO:0035035 - histone acetyltransferase binding GO:0043596 - nuclear replication fork GO:0043626 - PCNA complex GO:0045739 - positive regulation of DNA repair GO:0045740 - positive regulation of DNA replication GO:0070182 - DNA polymerase binding GO:0070557 - PCNA-p21 complex GO:0071466 - cellular response to xenobiotic stimulus GO:1902990 - mitotic telomere maintenance via semi-conservative replication
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1	261
Cg

1	261

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Last updated: 15 Jul 2024