HitPredict

Interactor 1: FBXW4 (P57775)
F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)
Gene: FBXW4

Interactor 2: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	23658844, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 327
+	Hs
		1185010 FBW1B_HUMAN (34-411): 3.49e-81: 260: 16.03		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00
+	Hs
		124819 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		EIF3F_HUMAN (10-306): 1.15e-110: 327: 22.07
+	Hs
		124920 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		EIF3F_HUMAN (10-306): 1.15e-110: 327: 22.07
+	Hs
		1185016 FBW1A_HUMAN (39-151): 6.54e-10: 62.9: 10.83		CSN6_HUMAN (1-327): 1.8e-141: 404: 100.00