Interactor 1: SESN2 (P58004)
Sestrin-2 (EC 1.11.1.-) (Hypoxia-induced gene)
Gene: SESN2
Interactor 2: CAST1 (Q8WTX7)
Cytosolic arginine sensor for mTORC1 subunit 1 (Cellular arginine sensor for mTORC1 protein 1) (GATS-like protein 3)
Gene: CASTOR1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.55 | 0.458 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35831510 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0034198 - cellular response to amino acid starvation GO:0140311 - protein sequestering activity GO:1904262 - negative regulation of TORC1 signaling GO:1904263 - positive regulation of TORC1 signaling |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
