Interactor 1: SESN3 (P58005)
Sestrin-3 (EC 1.11.1.-)
Gene: SESN3

Interactor 2: NPRL3 (Q12980)
GATOR1 complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA)
Gene: NPRL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.550

The method score is based on:

Property Details
Experiments 25263562
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0034198 - cellular response to amino acid starvation
GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 492
Hs

1 569
+ Hs

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Last updated: 15 Jul 2024