Interactor 1: PRI1 (P49642)
DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49)
Gene: PRIM1

Interactor 2: PRI2 (P49643)
DNA primase large subunit (DNA primase 58 kDa subunit) (p58)
Gene: PRIM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 28757209, 32296183, 28514442, 33961781, 39358380, unassigned1304
Identification Methods pull down, two hybrid, affinity chromatography technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_primase_S~DNA_primase_lrg
Common GO terms GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0006269 - DNA replication, synthesis of primer
GO:0006270 - DNA replication initiation
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 420
Hs

1 509
+ Dm
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025