Interactor 1: ATS12 (P58397)
A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-)
Gene: ADAMTS12

Interactor 2: ATS7 (Q9UKP4)
A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)
Gene: ADAMTS7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ADAMTS_CR_2~ADAMTS_CR_2, ADAMTS_CR_2~Reprolysin, ADAMTS_CR_2~TSP_1, ADAMTS_CR_3~ADAMTS_spacer1, ADAMTS_CR_3~TSP_1, Reprolysin~Reprolysin, TSP_1~TSP_1
Common GO terms GO:0002062 - chondrocyte differentiation
GO:0004222 - metalloendopeptidase activity
GO:0005576 - extracellular region
GO:0030198 - extracellular matrix organization
GO:0030199 - collagen fibril organization
and 8 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1594
Hs

1 1686
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Last updated: 15 Jul 2024