HitPredict

Interactor 1: NRX2B (P58401)
Neurexin-2-beta (Neurexin II-beta)
Gene: NRXN2

Interactor 2: NLGN1 (Q8N2Q7)
Neuroligin-1
Gene: NLGN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	8576240
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	COesterase~Laminin_G_2
Common GO terms	GO:0005886 - plasma membrane GO:0007158 - neuron cell-cell adhesion GO:0050839 - cell adhesion molecule binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 666 Hs			1 863
+	Hs
		1231772 NRX3A_HUMAN (85-666): 0: 837: 55.61		NLGN1_HUMAN (1-863): 0: 1158: 100.00
+	Rn
		1144053 NRX2A_RAT (86-666): 0: 1018: 97.94		NLGN2_RAT (49-863): 0: 864: 61.12
+	Hs
		1348964 NRX3A_HUMAN (85-666): 0: 837: 55.61		NLGN3_HUMAN (33-863): 0: 1033: 68.44
+	Hs
		885677 NRX2B_HUMAN (13-666): 0: 943: 100.00		NLGN2_HUMAN (49-863): 0: 855: 61.86
+	Hs
		1245092 NRX3A_HUMAN (85-666): 0: 837: 55.61		NLGN2_HUMAN (49-863): 0: 855: 61.86
+	Hs
		885667 NRX1B_HUMAN (566-666): 1.33e-44: 168: 83.33		NLGN1_HUMAN (1-863): 0: 1158: 100.00
+	Rn
		1144024 NRX1B_RAT (566-666): 5.01e-47: 174: 83.33		NLGN1_RAT (1-863): 0: 1121: 95.83
+	Rn
		1144060 NRX1A_RAT (566-666): 2.61e-45: 176: 83.33		NLGN3_RAT (33-863): 0: 1032: 68.68
+	Hs
		885671 NRX1B_HUMAN (566-666): 1.33e-44: 168: 83.33		NLGN3_HUMAN (33-863): 0: 1033: 68.44
+	Rn
		1144052 NRX1B_RAT (566-666): 5.01e-47: 174: 83.33		NLGN2_RAT (49-863): 0: 864: 61.12
+	Hs
		885668 NRX1B_HUMAN (566-666): 1.33e-44: 168: 83.33		NLGN2_HUMAN (49-863): 0: 855: 61.86
+	Dm
		1108397 NRX1_DROME (86-286): 2.12e-13: 76: 19.80		Q9VIC7_DROME (41-684): 5.76e-164: 514: 30.14
+	Dm
		1108393 NRX1_DROME (86-286): 2.12e-13: 76: 19.80		Q9NGK5_DROME (54-642): 1.04e-148: 471: 31.16