HitPredict

Interactor 1: UB2D1 (D3ZDK2)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: Ube2d1

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Rn			1 810
+	Xl
		919927 UB2D2_XENLA (1-147): 7.7e-82: 238: 89.12		Q7SY79_XENLA (229-801): 0: 702: 96.68
+	Hs
		476604 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475501 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475586 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475550 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476218 UB2E2_HUMAN (4-146): 3.11e-74: 221: 62.94		UBC_HUMAN (1-533): 0: 662: 99.81
+	Dm
		639414 UBCD1_DROME (1-147): 1.87e-81: 238: 89.12		Q9W418_DROME (305-801): 0: 604: 96.18
+	Sc
		477103 UBC4_YEAST (3-147): 3.9e-79: 232: 79.31		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	At
		1091932 UBC28_ARATH (1-147): 6.9e-83: 241: 76.19		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		715116 UBC8_ARATH (1-147): 3.61e-82: 239: 76.19		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		715157 UBC11_ARATH (1-147): 6.25e-82: 239: 76.19		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		715132 UBC9_ARATH (1-147): 8.78e-82: 238: 77.55		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		715147 UBC10_ARATH (1-147): 9.28e-82: 238: 76.87		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		895773 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		70479 UB2E3_HUMAN (4-146): 1.2e-73: 220: 62.94		B2RDW1_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		476737 UB2D3_MOUSE (1-147): 9.08e-81: 236: 88.44		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		171490 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		UBD_HUMAN (155-304): 2.44e-28: 113: 32.05
+	Hs
		397879 UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Hs
		475249 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		474984 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70