HitPredict

Interactor 1: MTPN (P58546)
Myotrophin (Protein V-1)
Gene: MTPN

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~CC2-LZ
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 419
+	Hs
		1309895 ACBD6_HUMAN (3-118): 2.37e-38: 131: 34.19		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		862142 DAPK1_HUMAN (2-87): 6.05e-24: 96.8: 27.91		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		1078921 RAI14_HUMAN (2-99): 2.66e-26: 103: 27.72		ITSN1_HUMAN (24-403): 1.07e-30: 127: 12.15
+	Hs
		965180 ANK2_HUMAN (1-87): 3.16e-30: 114: 31.03		MYO5A_HUMAN (38-342): 1.7e-24: 108: 14.65
+	Hs
		1219814 ANKH1_HUMAN (2-93): 1.32e-10: 58.9: 35.87		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		1216417 TNKS2_HUMAN (39-117): 4.37e-16: 74.5: 23.46		MY18B_HUMAN (35-415): 6.59e-31: 127: 13.46
+	Hs
		862127 DAPK1_HUMAN (2-87): 6.05e-24: 96.8: 27.91		MYO5B_HUMAN (64-394): 2.99e-18: 89.7: 16.95
+	Hs
		724782 ANK2_HUMAN (1-87): 3.16e-30: 114: 31.03		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		725139 ANK2_HUMAN (1-87): 3.16e-30: 114: 31.03		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09
+	Hs
		305108 ANR11_HUMAN (28-118): 3.98e-28: 108: 31.87		RIMB1_HUMAN (31-362): 3.69e-10: 64.3: 14.99
+	Hs
		725049 RAI14_HUMAN (2-99): 2.66e-26: 103: 27.72		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		1268104 RAI14_HUMAN (2-99): 2.66e-26: 103: 27.72		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89
+	Hs
		225128 MYPT2_HUMAN (4-87): 6.52e-20: 85.3: 27.38		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		225152 MYPT2_HUMAN (4-87): 6.52e-20: 85.3: 27.38		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89
+	Hs
		161319 MYPT1_HUMAN (4-87): 2.11e-16: 75.5: 25.00		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		161423 MYPT1_HUMAN (4-87): 2.11e-16: 75.5: 25.00		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89