Interactor 1: TIRAP (P58753)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein) (MyD88-2)
Gene: TIRAP
Interactor 2: TCAM2 (Q86XR7)
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)
Gene: TICAM2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 0.90 | 0.631 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12721283 |
| Identification Methods | affinity chromatography technology, coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TIR_2~TIR_2 |
| Common GO terms | GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0034142 - toll-like receptor 4 signaling pathway GO:0034145 - positive regulation of toll-like receptor 4 signaling pathway GO:0043123 - positive regulation of canonical NF-kappaB signal transduction and 2 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
