Interactor 1: TIRAP (P58753)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein) (MyD88-2)
Gene: TIRAP
Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28483816, 11544529, 17258210, 20048342, 33961781, 18221795, 24316379, 11526399, 12888566, 19506249, 21873236, 24265315, 21334391, 17583698 |
| Identification Methods | affinity chromatography technology, two hybrid, protein complementation assay, pull down, anti tag coimmunoprecipitation, mammalian protein protein interaction trap |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TIR_2~TIR_2 |
| Common GO terms | GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway and 14 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
