HitPredict

Interactor 1: FLNC (D3ZHA0)
Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: ANK3 (O70511)
Ankyrin-3 (ANK-3) (Ankyrin-G)
Gene: ANK3

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21223964
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0008092 - cytoskeletal protein binding GO:0030018 - Z disc GO:0042383 - sarcolemma GO:0043034 - costamere
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2726 Rn			1 2622
+	Hs
		1021400 FLNC_HUMAN (1-2726): 0: 2229: 98.24		ANK3_HUMAN (941-2622): 8e-49: 196: 20.69
+	Hs
		556695 SPTB2_HUMAN (5-267): 7.07e-106: 383: 35.77		ANK1_HUMAN (1-757): 0: 760: 33.11
+	Hs
		506803 SPTB1_HUMAN (38-258): 1.05e-35: 152: 38.33		ANK1_HUMAN (1-757): 0: 760: 33.11
+	Hs
		556706 OBSCN_HUMAN (820-1236): 1.79e-14: 82.5: 11.52		ANK1_HUMAN (1-757): 0: 760: 33.11
+	Hs
		556716 TITIN_HUMAN (829-1192): 6.85e-12: 74.1: 10.59		ANK1_HUMAN (1-757): 0: 760: 33.11
+	Hs
		166985 TITIN_HUMAN (829-1192): 6.85e-12: 74.1: 10.59		ANR28_HUMAN (1-561): 6.28e-160: 527: 24.62
+	Hs
		211682 ACTN4_HUMAN (17-355): 1.02e-103: 358: 28.12		ANFY1_HUMAN (477-996): 2.45e-63: 240: 18.18
+	Hs
		963306 SPTB2_HUMAN (5-267): 7.07e-106: 383: 35.77		ANK3_HUMAN (941-2622): 8e-49: 196: 20.69
+	Mm
		103603 SPTB2_MOUSE (5-267): 7.06e-106: 383: 35.77		ANK3_MOUSE (2257-2622): 6.76e-30: 133: 48.93
+	Mm
		103598 Q3UGX2_MOUSE (3-260): 8.78e-101: 366: 35.25		ANK3_MOUSE (2257-2622): 6.76e-30: 133: 48.93
+	Hs
		963292 SPTB2_HUMAN (5-267): 7.07e-106: 383: 35.77		ANK2_HUMAN (1795-2620): 4.72e-20: 100: 8.24
+	Hs
		965118 OBSCN_HUMAN (820-1236): 1.79e-14: 82.5: 11.52		ANK2_HUMAN (1795-2620): 4.72e-20: 100: 8.24