HitPredict

Interactor 1: D3ZHG8 (D3ZHG8)
Golgi associated, gamma adaptin ear containing, ARF binding protein 3
Gene: Gga3

Interactor 2: ARF6 (P62332)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26446845
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Arf~GGA_N-GAT
Common GO terms	GO:0006886 - intracellular protein transport GO:0031901 - early endosome membrane GO:0034394 - protein localization to cell surface
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 658 Rn			1 175
+	Rn
		88619 D3ZHG8_RAT (1-658): 4.06e-174: 513: 100.00		ARF1_RAT (2-175): 4.43e-69: 209: 68.39
+	Rn
		88617 D3ZHG8_RAT (1-658): 4.06e-174: 513: 100.00		ARF3_RAT (2-175): 4.91e-65: 198: 69.54
+	Hs
		950568 GGA3_HUMAN (1-658): 7.16e-150: 453: 76.49		ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39
+	Hs
		913149 GGA3_HUMAN (1-658): 7.16e-150: 453: 76.49		ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00
+	Hs
		897409 GGA3_HUMAN (1-658): 7.16e-150: 453: 76.49		ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54
+	Hs
		950575 GGA1_HUMAN (2-658): 1.14e-142: 431: 51.51		ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39
+	Hs
		950740 GGA1_HUMAN (2-658): 1.14e-142: 431: 51.51		ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12
+	Mm
		950589 GGA3_MOUSE (1-658): 3.61e-138: 422: 78.27		ARF1_MOUSE (2-175): 4.43e-69: 209: 68.39
+	Hs
		913175 GGA1_HUMAN (2-658): 1.14e-142: 431: 51.51		ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00
+	Hs
		897416 GGA1_HUMAN (2-658): 1.14e-142: 431: 51.51		ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54
+	Hs
		574772 GGA2_HUMAN (2-656): 1.47e-125: 386: 40.09		ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74
+	Hs
		950574 GGA2_HUMAN (2-656): 1.47e-125: 386: 40.09		ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39
+	Hs
		913174 GGA2_HUMAN (2-656): 1.47e-125: 386: 40.09		ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00
+	Hs
		897415 GGA2_HUMAN (2-656): 1.47e-125: 386: 40.09		ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54
+	Hs
		212618 AP1G1_HUMAN (16-655): 2.06e-97: 318: 15.54		ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39
+	Hs
		212615 AP1G1_HUMAN (16-655): 2.06e-97: 318: 15.54		ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00
+	Hs
		277049 STAM2_HUMAN (1-552): 2.13e-96: 308: 16.87		ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12
+	Dm
		778418 Q9W329_DROME (9-640): 3.47e-84: 280: 21.87		ARF6_DROME (1-174): 4e-68: 206: 97.13
+	Sc
		503143 GGA1_YEAST (2-499): 2.3e-74: 251: 21.86		ARF1_YEAST (2-175): 2.05e-68: 207: 66.09
+	Sc
		580871 GGA1_YEAST (2-499): 2.3e-74: 251: 21.86		ARF2_YEAST (2-175): 9.78e-65: 197: 66.09