Interactor 1: NALP5 (P59047)
NACHT, LRR and PYD domains-containing protein 5 (Mater protein homolog) (Maternal Antigen that Embryos Require)
Gene: NLRP5

Interactor 2: NALP2 (Q9NX02)
NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)
Gene: NLRP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 26496610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_6~LRR_6, NACHT~NACHT, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD2~NOD2_WH, PYRIN~PYRIN
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0043231 - intracellular membrane-bounded organelle
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1200
Hs

1 1062
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Last updated: 15 Jul 2024