HitPredict

Interactor 1: SPIKE (P59594)
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']
Gene: S

Interactor 2: VME1 (P59596)
Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)
Gene: M

Species: Severe acute respiratory syndrome-related coronavirus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	18792806, 20007283, 15507643
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019031 - viral envelope GO:0055036 - virion membrane
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 1255 Sa			1 221
+	Sa
		484750 SPIKE_SARS2 (1-1255): 0: 2384: 76.04		VME1_SARS2 (1-221): 2.79e-139: 390: 90.54