Interactor 1: AP3A (P59632)
ORF3a protein (Accessory protein 3a) (Protein 3a) (Protein U274) (Protein X1)
Gene: 3a

Interactor 2: AP3A (P59632)
ORF3a protein (Accessory protein 3a) (Protein 3a) (Protein U274) (Protein X1)
Gene: 3a

Species: Severe acute respiratory syndrome-related coronavirus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.911

The method score is based on:

Property Details
Experiments 16894145, 33845483, 36695574, 26579480
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, x-ray crystallography, pull down, protein complementation assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains bCoV_viroporin~bCoV_viroporin
Common GO terms GO:0005216 - monoatomic ion channel activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0005891 - voltage-gated calcium channel complex
GO:0008076 - voltage-gated potassium channel complex
and 7 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 274
Sa

1 274
+ Sa

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024