HitPredict

Interactor 1: DEF1 (P59665)
Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)]
Gene: DEFA1

Interactor 2: SULF2 (Q8IWU5)
Extracellular sulfatase Sulf-2 (hSulf-2) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]
Gene: SULF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 94 Hs			1 870
+	Hs
		965253 DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94		SULF2_HUMAN (1-870): 0: 1369: 100.00
+	Hs
		887045 DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00		ARSK_HUMAN (36-411): 8.12e-101: 325: 23.68
+	Hs
		550460 DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00		ARSB_HUMAN (36-439): 5.33e-98: 318: 18.06
+	Hs
		709243 DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00		GALNS_HUMAN (42-398): 7.14e-95: 309: 22.48