HitPredict

Interactor 1: DEF1 (P59665)
Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)]
Gene: DEFA1

Interactor 2: PLXA1 (Q9UIW2)
Plexin-A1 (Semaphorin receptor NOV)
Gene: PLXNA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 94 Hs			1 1896
+	Hs
		965269 DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94		PLXA1_HUMAN (1-1896): 0: 2610: 100.00
+	Hs
		253459 DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00		PLXA2_HUMAN (34-1896): 0: 2410: 63.96
+	Hs
		253461 DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94		PLXA2_HUMAN (34-1896): 0: 2410: 63.96
+	Hs
		165176 DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00		PLXB2_HUMAN (38-1893): 0: 1949: 32.31
+	Hs
		165191 DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94		PLXB2_HUMAN (38-1893): 0: 1949: 32.31