HitPredict

Interactor 1: HIF1N (P59723)
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase)
Gene: hif1an

Interactor 2: MIB1 (Q804S5)
E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Protein mind bomb) (RING-type E3 ubiquitin transferase mib1)
Gene: MIB1

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	24714733
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 344 Dr			1 1030
+	Dr
		47645 HIF1N_DANRE (1-344): 1.56e-139: 401: 100.00		A0AR23_DANRE (3-1030): 0: 688: 36.23
+	Hs
		1284696 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		MIB2_HUMAN (14-1030): 0: 659: 35.74
+	Hs
		1347416 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANR50_HUMAN (165-982): 4.75e-160: 511: 15.58
+	Hs
		1237555 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANR44_HUMAN (160-742): 3.42e-98: 334: 14.29
+	Hs
		1347414 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		KDIS_HUMAN (353-635): 1.38e-61: 232: 21.77
+	Hs
		167023 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANR28_HUMAN (193-551): 1.89e-57: 217: 14.46
+	Hs
		1244264 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANKK1_HUMAN (238-625): 5.7e-58: 216: 18.93
+	Hs
		1021468 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANK3_HUMAN (639-1021): 1.43e-49: 195: 13.32
+	Hs
		965164 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANK2_HUMAN (639-1021): 1.45e-47: 188: 13.27
+	Hs
		883653 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		RIPK4_HUMAN (433-718): 1.04e-24: 113: 30.77
+	Hs
		1330861 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		Q9H4D1_HUMAN (433-718): 2.92e-24: 111: 30.77
+	Hs
		1302643 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		Q96T11_HUMAN (433-718): 8.43e-24: 110: 30.77
+	Hs
		1239510 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANR52_HUMAN (129-435): 6.83e-21: 101: 8.33
+	Hs
		257711 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANR17_HUMAN (188-375): 2.02e-19: 96.8: 9.57
+	Hs
		310099 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		TNKS1_HUMAN (743-1017): 2.21e-19: 96.4: 11.58
+	Hs
		1219860 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		ANKH1_HUMAN (188-376): 7.18e-18: 91.8: 9.52
+	Hs
		1329536 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		TNKS2_HUMAN (743-1017): 8.72e-18: 91: 9.47
+	Hs
		1115389 HIF1N_HUMAN (10-340): 2.84e-131: 380: 83.38		AKD1A_HUMAN (432-630): 1.37e-09: 63.9: 27.72