HitPredict

Interactor 1: D3ZTD1 (D3ZTD1)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25)
Gene: Map3k14

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 942 Rn			1 810
+	Rn
		514950 KCC2G_RAT (400-925): 2.89e-135: 417: 16.73		UBC_RAT (1-810): 0: 1000: 100.00
+	Rn
		550163 KCC2D_RAT (400-924): 5.78e-133: 411: 16.58		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		476256 M3K14_HUMAN (1-942): 0: 746: 84.72		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475390 AKT1_HUMAN (272-711): 2.2e-135: 416: 19.74		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475703 M3K1_HUMAN (395-649): 5.6e-25: 114: 32.71		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476603 M3K2_HUMAN (372-651): 2.19e-23: 107: 30.80		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476266 M3K3_HUMAN (408-614): 9.82e-22: 102: 33.33		UBC_HUMAN (1-533): 0: 662: 99.81
+	At
		1091641 KIN10_ARATH (401-827): 2.28e-134: 414: 19.91		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		955189 KIN11_ARATH (401-847): 7.12e-128: 397: 18.26		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1091896 SRK2E_ARATH (390-702): 1.97e-100: 320: 26.85		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		681773 AKT1_HUMAN (272-711): 2.2e-135: 416: 19.74		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		474936 AKT2_HUMAN (272-712): 2.86e-138: 423: 20.56		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		474935 AKT1_HUMAN (272-711): 2.2e-135: 416: 19.74		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		475012 STK4_HUMAN (402-652): 3.87e-100: 323: 30.59		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		1306392 M3K3_HUMAN (408-614): 9.82e-22: 102: 33.33		Q9UFQ0_HUMAN (599-801): 2.76e-76: 248: 90.64
+	Hs
		924221 M3K2_HUMAN (372-651): 2.19e-23: 107: 30.80		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		924126 M3K3_HUMAN (408-614): 9.82e-22: 102: 33.33		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		475017 M3K1_HUMAN (395-649): 5.6e-25: 114: 32.71		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		475248 M3K2_HUMAN (372-651): 2.19e-23: 107: 30.80		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		475158 M3K3_HUMAN (408-614): 9.82e-22: 102: 33.33		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70