HitPredict

Interactor 1: KR121 (P59990)
Keratin-associated protein 12-1 (High sulfur keratin-associated protein 12.1) (Keratin-associated protein 12.1)
Gene: KRTAP12-1

Interactor 2: KRA44 (Q9BYR3)
Keratin-associated protein 4-4 (Keratin-associated protein 4-13) (Keratin-associated protein 4.13) (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.4)
Gene: KRTAP4-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045095 - keratin filament
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 96 Hs			1 166
+	Hs
		887328 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KRA13_HUMAN (2-165): 1.33e-27: 102: 36.36
+	Hs
		887295 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR122_HUMAN (28-166): 1.43e-26: 99.4: 34.29
+	Hs
		887302 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR109_HUMAN (3-156): 1.49e-24: 97.9: 33.14
+	Hs
		888526 KR123_HUMAN (1-96): 2e-33: 112: 76.04		KR109_HUMAN (3-156): 1.49e-24: 97.9: 33.14
+	Hs
		887298 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR103_HUMAN (2-141): 2.41e-23: 93.2: 34.42
+	Hs
		887299 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR105_HUMAN (14-166): 1.68e-22: 92.1: 33.33
+	Hs
		887300 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR107_HUMAN (11-165): 6.43e-20: 86.7: 26.34
+	Hs
		888524 KR123_HUMAN (1-96): 2e-33: 112: 76.04		KR107_HUMAN (11-165): 6.43e-20: 86.7: 26.34
+	Hs
		887335 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KRA45_HUMAN (3-166): 4.76e-19: 81.3: 46.95
+	Hs
		887301 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR108_HUMAN (19-165): 2.65e-18: 80.9: 28.81
+	Hs
		888525 KR123_HUMAN (1-96): 2e-33: 112: 76.04		KR108_HUMAN (19-165): 2.65e-18: 80.9: 28.81
+	Hs
		887333 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KRA93_HUMAN (2-151): 2.17e-17: 76.3: 37.42
+	Hs
		887297 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR101_HUMAN (32-166): 6.51e-15: 72: 30.22
+	Hs
		887334 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KRA92_HUMAN (3-116): 3.48e-12: 62.8: 43.36
+	Hs
		887327 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR111_HUMAN (10-164): 1.45e-11: 60.9: 27.10
+	Hs
		887303 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KRA11_HUMAN (2-106): 2.23e-10: 58.2: 30.19
+	Hs
		887294 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR121_HUMAN (51-137): 6.05e-10: 55.1: 31.03
+	Hs
		887296 KR121_HUMAN (1-96): 2.24e-34: 115: 100.00		KR123_HUMAN (34-126): 2.53e-09: 53.6: 31.18
+	Hs
		888523 KR123_HUMAN (1-96): 2e-33: 112: 76.04		KR123_HUMAN (34-126): 2.53e-09: 53.6: 31.18