Interactor 1: ARPC4 (P59998)
Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
Gene: ARPC4

Interactor 2: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.900

The method score is based on:

Property Details
Experiments 24981860, 28514442, 11741539, 33961781
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ARPC4~Actin
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0034314 - Arp2/3 complex-mediated actin nucleation
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 168
Hs

1 418
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ At
+ Sc

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Last updated: 15 Jul 2024