HitPredict

Interactor 1: D3ZUY8 (D3ZUY8)
AP-2 complex subunit alpha
Gene: Ap2a1

Interactor 2: AMPH (O08838)
Amphiphysin
Gene: AMPH

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16903783, 11382783
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 956 Rn			1 683
+	Hs
		321511 AP2A1_HUMAN (1-956): 0: 858: 95.09		AMPH_HUMAN (1-683): 5.24e-133: 409: 85.04
+	Rn
		139980 Q66HM2_RAT (1-956): 0: 836: 80.19		AMPH_RAT (1-683): 2.59e-140: 427: 100.00
+	Mm
		567528 AP2A2_MOUSE (1-956): 0: 832: 80.94		AMPH_MOUSE (1-683): 7.59e-140: 426: 93.61
+	Hs
		302118 AP2A2_HUMAN (1-956): 0: 822: 79.08		AMPH_HUMAN (1-683): 5.24e-133: 409: 85.04
+	Rn
		139975 AP2B1_RAT (36-951): 0: 654: 17.03		AMPH_RAT (1-683): 2.59e-140: 427: 100.00
+	Mm
		1186720 AP2B1_MOUSE (36-951): 0: 653: 17.03		AMPH_MOUSE (1-683): 7.59e-140: 426: 93.61
+	Hs
		827733 AP2B1_HUMAN (36-951): 0: 654: 17.03		AMPH_HUMAN (1-683): 5.24e-133: 409: 85.04
+	Hs
		827743 AP1B1_HUMAN (36-951): 0: 647: 17.33		AMPH_HUMAN (1-683): 5.24e-133: 409: 85.04
+	Hs
		321552 AP2A1_HUMAN (1-956): 0: 858: 95.09		ITSN1_HUMAN (94-682): 1.09e-43: 171: 12.25
+	Rn
		88754 D3ZUY8_RAT (1-956): 0: 885: 100.00		BIN1_RAT (385-683): 8.19e-30: 126: 22.93
+	Hs
		321533 AP2A1_HUMAN (1-956): 0: 858: 95.09		EP300_HUMAN (107-598): 2.51e-32: 136: 10.47
+	Hs
		302157 AP2A2_HUMAN (1-956): 0: 822: 79.08		ITSN1_HUMAN (94-682): 1.09e-43: 171: 12.25
+	Hs
		131189 AP2A1_HUMAN (1-956): 0: 858: 95.09		BIN1_HUMAN (348-682): 3.34e-27: 118: 21.73
+	Rn
		139993 Q66HM2_RAT (1-956): 0: 836: 80.19		BIN1_RAT (385-683): 8.19e-30: 126: 22.93
+	Hs
		302143 AP2A2_HUMAN (1-956): 0: 822: 79.08		EP300_HUMAN (107-598): 2.51e-32: 136: 10.47
+	Hs
		131185 AP2A2_HUMAN (1-956): 0: 822: 79.08		BIN1_HUMAN (348-682): 3.34e-27: 118: 21.73
+	Hs
		925876 AP2B1_HUMAN (36-951): 0: 654: 17.03		ITSN1_HUMAN (94-682): 1.09e-43: 171: 12.25
+	Hs
		925856 AP2B1_HUMAN (36-951): 0: 654: 17.03		EP300_HUMAN (107-598): 2.51e-32: 136: 10.47
+	Rn
		139988 AP2B1_RAT (36-951): 0: 654: 17.03		BIN1_RAT (385-683): 8.19e-30: 126: 22.93
+	Hs
		925892 AP2B1_HUMAN (36-951): 0: 654: 17.03		SH319_HUMAN (244-682): 4.72e-27: 119: 15.25