HitPredict

Interactor 1: D3ZUY8 (D3ZUY8)
AP-2 complex subunit alpha
Gene: Ap2a1

Interactor 2: EPN1 (O88339)
Epsin-1 (EPS-15-interacting protein 1)
Gene: EPN1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16903783, 12234931
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035615 - clathrin adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 956 Rn			1 575
+	Hs
		321680 AP2A1_HUMAN (1-956): 0: 858: 95.09		EPN1_HUMAN (1-575): 2e-90: 291: 94.44
+	Rn
		291395 Q66HM2_RAT (1-956): 0: 836: 80.19		EPN1_RAT (1-575): 2.97e-96: 306: 100.00
+	Rn
		291387 AP2A2_RAT (1-956): 0: 831: 80.83		EPN1_RAT (1-575): 2.97e-96: 306: 100.00
+	Hs
		321545 AP2A1_HUMAN (1-956): 0: 858: 95.09		EPN4_HUMAN (3-560): 2.7e-80: 266: 25.43
+	Hs
		302230 AP2A2_HUMAN (1-956): 0: 822: 79.08		EPN1_HUMAN (1-575): 2e-90: 291: 94.44
+	Hs
		302148 AP2A2_HUMAN (1-956): 0: 822: 79.08		EPN4_HUMAN (3-560): 2.7e-80: 266: 25.43
+	Rn
		94317 Q66HM2_RAT (1-956): 0: 836: 80.19		F1M241_RAT (138-574): 2.49e-31: 131: 18.83
+	Dm
		954828 AP2A_DROME (3-956): 0: 777: 67.26		Q7KU90_DROME (1-563): 8.23e-50: 186: 31.30
+	Rn
		291389 AP2B1_RAT (36-951): 0: 654: 17.03		EPN1_RAT (1-575): 2.97e-96: 306: 100.00
+	Hs
		926065 AP2B1_HUMAN (36-951): 0: 654: 17.03		EPN1_HUMAN (1-575): 2e-90: 291: 94.44
+	Hs
		1014105 AP1B1_HUMAN (36-951): 0: 647: 17.33		EPN1_HUMAN (1-575): 2e-90: 291: 94.44
+	At
		1228257 AP2A1_ARATH (8-956): 0: 703: 37.08		EPN1_ARATH (2-448): 1.01e-65: 226: 21.35
+	Hs
		925867 AP2B1_HUMAN (36-951): 0: 654: 17.03		EPN4_HUMAN (3-560): 2.7e-80: 266: 25.43
+	Hs
		1014011 AP1B1_HUMAN (36-951): 0: 647: 17.33		EPN4_HUMAN (3-560): 2.7e-80: 266: 25.43
+	Dm
		1096902 Q24253_DROME (36-951): 0: 609: 15.74		Q8IN05_DROME (3-430): 5.86e-87: 296: 27.01
+	Sc
		743416 AP2A_YEAST (10-954): 0: 673: 25.94		ENT1_YEAST (3-225): 5.58e-63: 215: 37.22
+	Rn
		923862 AP2B1_RAT (36-951): 0: 654: 17.03		EPN2_RAT (1-572): 2.92e-65: 225: 43.17
+	At
		1147101 AP2A1_ARATH (8-956): 0: 703: 37.08		EPN2_ARATH (2-573): 5.3e-39: 154: 19.69
+	Hs
		307524 AP2B1_HUMAN (36-951): 0: 654: 17.03		EPN2_HUMAN (1-565): 9.06e-52: 189: 35.27
+	Dm
		1096905 Q24253_DROME (36-951): 0: 609: 15.74		Q9VD13_DROME (3-566): 5.49e-67: 231: 22.50