HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: TSN5 (P62079)
Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9)
Gene: TSPAN5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26686862
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0072659 - protein localization to plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 268
+	Hs
		887904 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		TSN14_HUMAN (1-266): 3.18e-84: 254: 58.27
+	Hs
		905534 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		TSN14_HUMAN (1-266): 3.18e-84: 254: 58.27
+	Hs
		326050 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		TSN15_HUMAN (14-263): 1.8e-61: 197: 34.00
+	Hs
		653089 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD82_HUMAN (11-267): 6.94e-60: 192: 28.09
+	Hs
		209300 TSN6_HUMAN (1-234): 4.88e-57: 183: 22.13		TSN15_HUMAN (14-263): 1.8e-61: 197: 34.00
+	Hs
		819444 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD151_HUMAN (5-266): 2.12e-56: 182: 22.64
+	Hs
		326051 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		TSN15_HUMAN (14-263): 1.8e-61: 197: 34.00
+	Hs
		326042 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		TSN15_HUMAN (14-263): 1.8e-61: 197: 34.00
+	Hs
		653088 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		CD82_HUMAN (11-267): 6.94e-60: 192: 28.09
+	Hs
		887757 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD81_HUMAN (12-264): 9.13e-50: 165: 22.99
+	Hs
		819445 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		CD151_HUMAN (5-266): 2.12e-56: 182: 22.64
+	Hs
		111521 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		K4DIA7_HUMAN (5-243): 1.4e-48: 162: 22.73
+	Hs
		602238 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD9_HUMAN (11-265): 6.79e-48: 160: 24.32
+	Hs
		279369 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		TSN9_HUMAN (13-268): 5.03e-54: 176: 24.42
+	Hs
		156137 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		TSN4_HUMAN (15-261): 1.67e-46: 157: 25.70
+	Hs
		583868 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD53_HUMAN (15-263): 2.01e-44: 151: 23.29
+	Hs
		602239 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		CD9_HUMAN (11-265): 6.79e-48: 160: 24.32
+	Hs
		602230 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		CD9_HUMAN (11-265): 6.79e-48: 160: 24.32
+	Hs
		237719 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		TSN2_HUMAN (14-155): 1.9e-14: 72.4: 34.93