HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: S39AE (Q15043)
Metal cation symporter ZIP14 (LIV-1 subfamily of ZIP zinc transporter 4) (LZT-Hs4) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14)
Gene: SLC39A14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30024968, 32900848
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 492
+	Hs
		905514 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		S39AE_HUMAN (1-492): 1.31e-155: 453: 100.00
+	Hs
		602257 CD9_HUMAN (1-234): 3.88e-53: 172: 43.59		S39AE_HUMAN (1-492): 1.31e-155: 453: 100.00
+	Hs
		326069 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		S39AE_HUMAN (1-492): 1.31e-155: 453: 100.00
+	Hs
		887981 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		S39AA_HUMAN (40-489): 6.43e-117: 364: 26.34
+	Hs
		887835 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		S39A6_HUMAN (63-489): 2.6e-102: 324: 26.53
+	Hs
		326251 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		S39AA_HUMAN (40-489): 6.43e-117: 364: 26.34
+	Hs
		326205 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		S39A8_HUMAN (42-491): 2.59e-101: 313: 49.22