HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: CADM1 (Q9BY67)
Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
Gene: CADM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32900848
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 442
+	Hs
		887960 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		NECT3_HUMAN (52-439): 4.89e-73: 240: 23.25
+	Hs
		887903 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CADM4_HUMAN (45-442): 2.31e-72: 234: 34.93
+	Hs
		602285 CD9_HUMAN (1-234): 3.88e-53: 172: 43.59		NECT3_HUMAN (52-439): 4.89e-73: 240: 23.25
+	Hs
		888000 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		602297 CD9_HUMAN (1-234): 3.88e-53: 172: 43.59		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		887918 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		NECT2_HUMAN (109-334): 8.32e-15: 78.2: 27.07
+	Hs
		2727 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		A0A0C4DG49_HUMAN (95-336): 1.06e-14: 77.4: 28.35
+	Hs
		545090 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		PVR_HUMAN (95-336): 1.06e-14: 77.4: 28.35
+	Hs
		1199563 TSN33_HUMAN (9-233): 7.63e-51: 168: 22.78		TITIN_HUMAN (135-439): 9.8e-09: 59.9: 14.38
+	Dm
		52381 Q7KJ73_DROME (3-234): 3.84e-44: 149: 21.37		A1Z7J1_DROME (104-322): 2.99e-12: 70.9: 25.76