Interactor 1: D3ZVH5 (D3ZVH5)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27)
Gene: Mdm2

Interactor 2: SUMO1 (Q5I0H3)
Small ubiquitin-related modifier 1 (SUMO-1)
Gene: SUMO1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 17000718
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0019899 - enzyme binding
GO:0031625 - ubiquitin protein ligase binding
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045892 - negative regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 458
Rn

1 101
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024