HitPredict

Interactor 1: H11 (D4A3K5)
Histone H1.1 (Histone H1a)
Gene: H1-1

Interactor 2: CDK1 (P39951)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9344597
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0030261 - chromosome condensation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 214 Rn			1 297
+	Rn
		413197 H1T_RAT (1-209): 2.82e-38: 133: 45.93		Q6P751_RAT (1-297): 8.56e-161: 450: 64.31
+	Hs
		559328 H13_HUMAN (1-182): 7.2e-25: 99: 51.65		CDK2_HUMAN (1-297): 3.45e-161: 452: 64.65
+	Rn
		88903 H11_RAT (1-181): 6.29e-25: 99: 100.00		Q6P751_RAT (1-297): 8.56e-161: 450: 64.31
+	Hs
		558990 H15_HUMAN (1-117): 2.62e-20: 87.1: 67.80		CDK2_HUMAN (1-297): 3.45e-161: 452: 64.65
+	Hs
		625377 H11_HUMAN (40-145): 1.11e-16: 77.1: 76.15		CDK2_HUMAN (1-297): 3.45e-161: 452: 64.65
+	Mm
		794656 H15_MOUSE (17-197): 1.49e-21: 90.2: 55.85		CDK2_MOUSE (1-297): 4.06e-152: 430: 55.36
+	Hs
		414717 H13_HUMAN (1-182): 7.2e-25: 99: 51.65		CDK1_HUMAN (1-297): 9.48e-148: 417: 97.64
+	Mm
		794643 H11_MOUSE (1-124): 4.03e-19: 83.6: 92.74		CDK2_MOUSE (1-297): 4.06e-152: 430: 55.36
+	Mm
		550489 H12_MOUSE (34-117): 6.04e-17: 77.8: 82.14		CDK2_MOUSE (1-297): 4.06e-152: 430: 55.36
+	Hs
		414716 H15_HUMAN (1-117): 2.62e-20: 87.1: 67.80		CDK1_HUMAN (1-297): 9.48e-148: 417: 97.64
+	Mm
		509472 H11_MOUSE (1-124): 4.03e-19: 83.6: 92.74		CDK1_MOUSE (1-297): 1.82e-146: 414: 99.33
+	Hs
		414874 H11_HUMAN (40-145): 1.11e-16: 77.1: 76.15		CDK1_HUMAN (1-297): 9.48e-148: 417: 97.64
+	Mm
		509461 H12_MOUSE (34-117): 6.04e-17: 77.8: 82.14		CDK1_MOUSE (1-297): 1.82e-146: 414: 99.33
+	Hs
		559654 H12_HUMAN (1-175): 1.09e-22: 92.8: 52.57		CDK5_HUMAN (1-293): 2.82e-138: 393: 56.46
+	Hs
		489003 H14_HUMAN (1-148): 1.58e-21: 90.2: 58.11		CDK5_HUMAN (1-293): 2.82e-138: 393: 56.46
+	Hs
		559065 H15_HUMAN (1-117): 2.62e-20: 87.1: 67.80		CDK5_HUMAN (1-293): 2.82e-138: 393: 56.46
+	Mm
		794639 H11_MOUSE (1-124): 4.03e-19: 83.6: 92.74		CDK5_MOUSE (1-293): 4.37e-138: 393: 56.46
+	Hs
		960270 H11_HUMAN (40-145): 1.11e-16: 77.1: 76.15		CDK5_HUMAN (1-293): 2.82e-138: 393: 56.46