Interactor 1: VEGFB (P49765)
Vascular endothelial growth factor B (VEGF-B) (VEGF-related factor) (VRF)
Gene: VEGFB

Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments unassigned3799
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0010629 - negative regulation of gene expression
GO:0016020 - membrane
GO:0043066 - negative regulation of apoptotic process
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 207
Hs

1 2471
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025