HitPredict

Interactor 1: SC61B (P60468)
Protein transport protein Sec61 subunit beta
Gene: SEC61B

Interactor 2: TMX3 (Q96JJ7)
Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3)
Gene: TMX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	32788342, 34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 96 Hs			1 454
+	Hs
		890381 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		ERP44_HUMAN (2-385): 5.2e-72: 234: 17.04
+	Hs
		890162 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		PDIA6_HUMAN (2-365): 1.77e-62: 210: 17.06
+	Hs
		671770 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		PDIA3_HUMAN (14-136): 6.09e-23: 103: 30.47
+	Hs
		531776 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		PDIA4_HUMAN (10-130): 1.56e-21: 99.5: 25.20
+	Hs
		423193 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		PDIA1_HUMAN (23-128): 2.75e-21: 98.3: 29.73
+	Hs
		890268 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		TXND5_HUMAN (45-125): 7.66e-12: 68.9: 37.81
+	Zm
		74708 B4FEC8_MAIZE (55-96): 1.53e-16: 69.5: 45.24		Q5EUD8_MAIZE (10-149): 1.74e-15: 80.6: 22.60