HitPredict

Interactor 1: SC61B (P60468)
Protein transport protein Sec61 subunit beta
Gene: SEC61B

Interactor 2: SEC63 (Q9UGP8)
Translocation protein SEC63 homolog (DnaJ homolog subfamily C member 23)
Gene: SEC63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	33957083, 32788342, 34079125, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005783 - endoplasmic reticulum GO:0016020 - membrane GO:0031204 - post-translational protein targeting to membrane, translocation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 96 Hs			1 760
+	Sc
		541760 SC6B2_YEAST (11-94): 2.33e-28: 99.5: 21.43		SEC63_YEAST (6-521): 5.25e-86: 287: 20.40
+	Sc
		541759 SC6B1_YEAST (22-93): 7.22e-20: 77.9: 23.68		SEC63_YEAST (6-521): 5.25e-86: 287: 20.40
+	Hs
		890466 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		DJB12_HUMAN (81-218): 1.24e-40: 155: 27.66
+	Hs
		890527 SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00		DJC16_HUMAN (74-166): 3.35e-24: 110: 33.33
+	Bt
		90456 Q2NKT5_BOVIN (1-96): 8.47e-32: 108: 98.96		E1B7B1_BOVIN (1-73): 1.55e-18: 92.3: 98.63