HitPredict

Interactor 1: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	9837938
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 307 Hs			1 619
+	Hs
		890953 PP4C_HUMAN (1-307): 0: 536: 100.00		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		915168 PP2AB_HUMAN (6-307): 0: 523: 65.23		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		930811 PP2AA_HUMAN (6-307): 0: 522: 65.89		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		587487 PP4C_HUMAN (1-307): 0: 536: 100.00		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		905877 PP1A_HUMAN (2-304): 0: 517: 43.89		NFAC2_HUMAN (1-504): 1.26e-88: 296: 14.84
+	Mm
		906254 PP1A_MOUSE (2-304): 0: 518: 44.20		SC31A_MOUSE (265-590): 7.02e-52: 195: 10.85
+	Hs
		302276 PP1A_HUMAN (2-304): 0: 517: 43.89		SC31A_HUMAN (266-590): 1.42e-36: 148: 11.11
+	Hs
		90115 PP1A_HUMAN (2-304): 0: 517: 43.89		D6REX3_HUMAN (266-590): 3.08e-32: 135: 9.43