HitPredict

Interactor 1: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Interactor 2: 2ABD (Q66LE6)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta)
Gene: PPP2R2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	33961781, 28514442, 28330616, 19156129
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 307 Hs			1 453
+	Hs
		915218 PP2AB_HUMAN (6-307): 0: 523: 65.23		2ABD_HUMAN (1-453): 0: 873: 100.00
+	Hs
		930887 PP2AA_HUMAN (6-307): 0: 522: 65.89		2ABD_HUMAN (1-453): 0: 873: 100.00
+	Hs
		890945 PP4C_HUMAN (1-307): 0: 536: 100.00		2ABA_HUMAN (1-453): 0: 838: 87.86
+	Hs
		915156 PP2AB_HUMAN (6-307): 0: 523: 65.23		2ABA_HUMAN (1-453): 0: 838: 87.86
+	Mm
		915330 PP2AB_MOUSE (6-307): 0: 523: 65.23		2ABA_MOUSE (1-453): 0: 838: 87.86
+	Hs
		927793 PP2AA_HUMAN (6-307): 0: 522: 65.89		2ABA_HUMAN (1-453): 0: 838: 87.86
+	Xl
		1153591 Q8AVH9_XENLA (6-307): 0: 521: 65.56		Q6IRD3_XENLA (1-453): 0: 827: 84.99
+	Hs
		890952 PP4C_HUMAN (1-307): 0: 536: 100.00		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Dm
		619858 PP2A_DROME (2-307): 0: 522: 64.05		2ABA_DROME (6-451): 0: 805: 78.25
+	Hs
		915163 PP2AB_HUMAN (6-307): 0: 523: 65.23		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Hs
		891015 PP4C_HUMAN (1-307): 0: 536: 100.00		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Hs
		930805 PP2AA_HUMAN (6-307): 0: 522: 65.89		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Xl
		50761 Q92140_XENLA (6-307): 0: 522: 65.89		2ABB_XENLA (32-453): 0: 794: 87.92
+	Xl
		50750 Q8AVH9_XENLA (6-307): 0: 521: 65.56		2ABB_XENLA (32-453): 0: 794: 87.92
+	Hs
		915310 PP2AB_HUMAN (6-307): 0: 523: 65.23		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Hs
		931049 PP2AA_HUMAN (6-307): 0: 522: 65.89		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Ce
		106202 PP2A_CAEEL (2-307): 0: 523: 63.73		2AB1_CAEEL (12-450): 0: 707: 65.20
+	Sp
		619316 PP2A2_SCHPO (2-307): 0: 507: 63.40		2ABA_SCHPO (17-449): 0: 668: 56.30
+	Sc
		618793 PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98		2ABA_YEAST (382-449): 2.2e-09: 61.6: 38.57