HitPredict

Interactor 1: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Interactor 2: TCPW (Q92526)
T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (CCT-zeta-like) (Chaperonin containing T-complex polypeptide 1 subunit 6B) (TCP-1-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303)
Gene: CCT6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 307 Hs			1 530
+	Hs
		890997 PP4C_HUMAN (1-307): 0: 536: 100.00		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		770761 PP4C_HUMAN (1-307): 0: 536: 100.00		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		915267 PP2AB_HUMAN (6-307): 0: 523: 65.23		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		930969 PP2AA_HUMAN (6-307): 0: 522: 65.89		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		826591 PP4C_HUMAN (1-307): 0: 536: 100.00		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Hs
		770775 PP2AB_HUMAN (6-307): 0: 523: 65.23		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		770782 PP2AA_HUMAN (6-307): 0: 522: 65.89		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		821143 PP4C_HUMAN (1-307): 0: 536: 100.00		TCPE_HUMAN (3-527): 0: 541: 30.34
+	Hs
		770772 PP1A_HUMAN (2-304): 0: 517: 43.89		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		826603 PP2AB_HUMAN (6-307): 0: 523: 65.23		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Hs
		826610 PP2AA_HUMAN (6-307): 0: 522: 65.89		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Hs
		821154 PP2AB_HUMAN (6-307): 0: 523: 65.23		TCPE_HUMAN (3-527): 0: 541: 30.34
+	Hs
		821161 PP2AA_HUMAN (6-307): 0: 522: 65.89		TCPE_HUMAN (3-527): 0: 541: 30.34
+	Sc
		618774 PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98		TCPZ_YEAST (3-530): 0: 555: 54.53
+	Sc
		618781 PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98		TCPH_YEAST (4-527): 0: 533: 25.61
+	Sc
		618772 PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98		TCPG_YEAST (2-527): 0: 530: 27.64
+	Sc
		688117 PP4C_YEAST (6-307): 7.03e-149: 421: 63.07		TCPG_YEAST (2-527): 0: 530: 27.64
+	Hs
		573192 PP4C_HUMAN (1-307): 0: 536: 100.00		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68
+	Hs
		573203 PP2AB_HUMAN (6-307): 0: 523: 65.23		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68
+	Hs
		573211 PP2AA_HUMAN (6-307): 0: 522: 65.89		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68