HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	20562859
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 491
+	Hs
		306153 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		STK3_HUMAN (1-491): 1.83e-172: 496: 100.00
+	Hs
		1027427 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		STK3_HUMAN (1-491): 1.83e-172: 496: 100.00
+	Hs
		1027422 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		STK3_HUMAN (1-491): 1.83e-172: 496: 100.00
+	Hs
		1027430 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		STK3_HUMAN (1-491): 1.83e-172: 496: 100.00
+	Hs
		1027423 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		STK3_HUMAN (1-491): 1.83e-172: 496: 100.00
+	Hs
		891118 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		306146 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		1023108 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		1023104 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		1023110 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		1023105 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		891114 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		M4K2_HUMAN (14-310): 3.14e-73: 249: 42.11
+	Hs
		306141 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		M4K2_HUMAN (14-310): 3.14e-73: 249: 42.11
+	Hs
		1018189 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		M4K2_HUMAN (14-310): 3.14e-73: 249: 42.11