HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	25684205, 20562859
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 768
+	Hs
		306162 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042509 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042457 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042492 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		CUL3_HUMAN (1-768): 0: 951: 100.00