HitPredict

Interactor 1: UB2G2 (P60604)
Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)
Gene: UBE2G2

Interactor 2: OTUB1 (Q96FW1)
Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1)
Gene: OTUB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	26752685, unassigned1260
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Peptidase_C65~UQ_con
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 271
+	Hs
		1291615 UB2D4_HUMAN (4-164): 2.75e-74: 220: 36.03		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		849408 UB2D1_HUMAN (4-164): 3.3e-73: 217: 36.03		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		919824 UB2D2_HUMAN (4-164): 5.65e-73: 217: 36.03		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		895878 UB2D3_HUMAN (4-164): 1.16e-71: 213: 34.78		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Ce
		715115 UBC2_CAEEL (4-164): 2.9e-73: 218: 34.78		OTUBL_CAEEL (3-271): 2.76e-122: 352: 34.42
+	Dm
		1369732 Q9VXE8_DROME (1-165): 1.98e-72: 216: 81.82		OTUBL_DROME (27-270): 3.47e-117: 338: 56.40